New Data Show Consistent Efficacy And Tolerability Of Trexima(R) (sumatriptan Succinate/naproxen Sodium) Across Multiple Migraine Attacks Part 2

About the Studies Consistent Efficacy Across Four Migraine Attacks Two painstaking cross-over clinical trial be conduct contained by adults near multiple migraine raid. The trials were randomized, multi-center, double-blind, placebo-controlled, and utilize precipitate negotiation (treating calm migraine agony and in one hour of the creation of pain).

Subjects were randomized to one of five coverage lock up and train to immoderation four migraine attacks. Patients in four group received sumatriptan/naproxen sodium in three of four attacks and placebo in the vanished done attack. Patients in the fifth contingent received sumatriptan/naproxen sodium in favour of all four attacks. The foremost analyses nearly new repetitive measures technique across attacks for both pain application at two hours and unlimited through 24 hours (co-primaries).

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- The percentage of patients who were pain exonerate at two hours be 52 percent and 25 percent (p<0.001) for sumatriptan/naproxen sodium and placebo, respectively.

- The percentage of patients who were sustained pain free at 24 hours was 37 percent and 17 percent (p<0.001) for sumatriptan/naproxen sodium and placebo, respectively.

In the second consistency study: - Five-hundred and sixty-five (565) patients treated 1,678 attacks with sumatriptan/naproxen sodium and 422 attacks with placebo.

- The percentage of patients who were pain free at two hours was 50 percent and 20 percent (p<0.001) for sumatriptan/naproxen sodium and placebo, respectively.

- The percentage of patients who were sustained pain free at 24 hours was 34 percent and 12 percent (p<0.001) for sumatriptan/naproxen sodium and placebo, respectively.

Adverse trial were unanimously mild with the best normal female bone-dry oral cavity, nausea, and wooziness across all attacks treated in both study. No vast drug-related adverse events were tale.

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