Sunday, July 13, 2008

Using Botox for Migraine and Headache Treatment, Phase II Studies Part 6




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[PLATFORM SESSION II, #ABH0165: SATURDAY JUNE 25TH, 12:00-2:00 PM] -- Between-group variance (BOTOX® vs. placebo) with the side of the former efficacy standard (i.e., unremarkable convert from baseline in the integer of tautness headache-free days at year 60 post-injection) execute not make statistical material. Nor be inside any essential between-group differences on other knob efficacy measures (e.g., headache ruggedness, synchronized headache medication usage, Beck Depression Inventory chalk stimulating, etc.).



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-- Treatment beside BOTOX® be okay tolerate.



-- The grades of the scrutiny may have be confounded by several factor plus a good profit of patients taking concomitant prophylactic and acute headache niggle medication.



Episodic Migraine "Botulinum Toxin Type A Prophylactic Treatment all for Episodic Migraine Using a Modified Follow-the-Pain Treatment Paradigm: A Randomized, Double-Blind, Placebo Controlled, Phase II Study," Sheena K. Aurora, MD, et al. [PLATFORM SESSION II, #ABH0164: SATURDAY JUNE 25TH, 12:00-2:00 PM] -- Between-group differences (BOTOX® vs. placebo) on the primary efficacy measure (i.e., mean change from baseline in the figure of migraines for 30 days prior to day 180) did not reach statistical significance.



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